Название продукции:Spiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'(1'H)-one dihydrochloride
IUPAC Name:1',2'-dihydrospiro[piperidine-4,3'-pyrrolo[2,3-b]pyridin]-2'-one dihydrochloride
- CAS：883984-94-9
- Молекулярная формула：C11H15Cl2N3O
- Чистота：95%
- Номер в каталоге：CM217995
- Молекулярная масса：276.16
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Информация о продукции
- Номер CAS:883984-94-9
- Молекулярная формула:C11H15Cl2N3O
- Точка плавления:-
- Smiles-код:O=C1NC2=NC=CC=C2C31CCNCC3.[H]Cl.[H]Cl
- Плотность:
- Номер в каталоге:CM217995
- Молекулярная масса:276.16
- Точка кипения:
- Номер Mdl:
- Хранение:
Category Infos
- Piperidines
- Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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- Spiro Compounds
- A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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- Azaindoles
- Azaindole can be regarded as the biological isostere of indole, and the molecular unit of indole plays a huge role in the life process. Many drug molecules contain indole units. Azaindole is an important heterocyclic intermediate with good biological and medicinal value, and is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, kinase inhibitors, thrombin inhibitors, etc. Therefore, it has a wide range of application value in medical research. Azaindole can be regarded as the biological isostere of indole, and the molecular unit of indole plays a huge role in the life process. Many drug molecules contain indole units. Azaindole is an important heterocyclic intermediate with good biological and medicinal value, and is the core structure of many drugs, such as antitumor drugs, dopamine D4 receptors, kinase inhibitors, thrombin inhibitors, etc. Therefore, it has a wide range of application value in medical research.Azaindole
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