Название продукции:2-Ethylbutyric Acid
IUPAC Name:2-ethylbutanoic acid
- CAS:88-09-5
- Молекулярная формула:C6H12O2
- Чистота:95%+
- Номер в каталоге:CM394240
- Молекулярная масса:116.16
Только для использования в НИОКР..
Информация о продукции
- Номер CAS:88-09-5
- Молекулярная формула:C6H12O2
- Точка плавления:-
- Smiles-код:CCC(CC)C(O)=O
- Плотность:
- Номер в каталоге:CM394240
- Молекулярная масса:116.16
- Точка кипения:
- Номер Mdl:
- Хранение:
Column Infos
- KB-0742
- Kronos Bio announces the first patient dosed in an expansion cohort with KB-0742 at a dose of 80mg given on a four-days-on, three-days-off schedule. This expansion cohort is enrolling platinum-resistant patients with high-grade serous ovarian cancer (HGSOC). Many cancers exhibit transcriptional deregulation, often characterized by gene amplifications of MYC family oncogene. Targeting the transcription elongation cofactor, cyclin-dependent kinase 9 (CDK9) has emerged as a therapeutic strategy to disrupt MYC oncogenic activity.
KB-0742 is an oral highly selective CDK9 inhibitor designed for the treatment of patients with MYC-amplified and other transcriptionally addicted relapsed or refractory solid tumors, including ovarian, lung, and triple-negative breast cancers.