Название продукции:4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine
IUPAC Name:4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine
- CAS:876343-10-1
- Молекулярная формула:C6H3ClIN3
- Чистота:95%+
- Номер в каталоге:CM104043
- Молекулярная масса:279.47
Только для использования в НИОКР..
Информация о продукции
- Номер CAS:876343-10-1
- Молекулярная формула:C6H3ClIN3
- Точка плавления:-
- Smiles-код:ClC1=C2C=C(I)NC2=NC=N1
- Плотность:
- Номер в каталоге:CM104043
- Молекулярная масса:279.47
- Точка кипения:
- Номер Mdl:MFCD11518919
- Хранение:-20°C
Category Infos
- Pyrrolopyrimidines
- Fusion heterocyclic compounds have various biological activities, such as anticancer, antibacterial, antifungal and anti-inflammatory, and thus have been widely used in the field of medicinal chemistry. Pyrrolopyrimidines are a major class of fused heterocyclic compounds. Compared with single pyrrole and pyrimidine cores, pyrrolopyrimidines have more diverse and effective pharmacological characteristics as fusion scaffolds.
Column Infos
- BMF-219
- Biomea Fusion’s BMF-219 demonstrates promising early signs of clinical activity, with its ability to achieve durable and sustained complete responses (CRs) and minimal residual disease negativity (MRD-neg) in patients with acute myeloid leukemia (AML). Biomea Fusion recently presents this First Complete Responder from Ongoing Phase I Study at the 2023 ASH.
BMF-219 is the first and only covalent menin inhibitor in clinical development for AML, ALL, DLBCL, MM and CLL. Additionally, BMF-219 is being explored for its potential to regenerate insulin-producing beta cells as a treatment of type 1 diabetes.