Название продукции:3-Cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione

IUPAC Name:3-cyclopropyl-1-(2-fluoro-4-iodophenyl)-5-hydroxy-6,8-dimethyl-1H,2H,3H,4H,7H,8H-pyrido[2,3-d]pyrimidine-2,4,7-trione

CAS:871700-24-2
Молекулярная формула:C18H15FIN3O4
Чистота:97%
Номер в каталоге:CM167869
Молекулярная масса:483.24

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Информация о продукции

Номер CAS:871700-24-2
Молекулярная формула:C18H15FIN3O4
Точка плавления:-
Smiles-код:O=C1N(C2=CC=C(I)C=C2F)C3=C(C(O)=C(C)C(N3C)=O)C(N1C4CC4)=O
Плотность:
Номер в каталоге:CM167869
Молекулярная масса:483.24
Точка кипения:518.2±60.0°C at 760 mmHg
Номер Mdl:MFCD18207185
Хранение:Keep in dark place, store at 2-8°C.

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.