Название продукции:(2-Fluoro-6-isopropoxyphenyl)boronic acid

IUPAC Name:[2-fluoro-6-(propan-2-yloxy)phenyl]boronic acid

CAS:870777-17-6
Молекулярная формула:C9H12BFO3
Чистота:95%+
Номер в каталоге:CM137244
Молекулярная масса:198

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Информация о продукции

Номер CAS:870777-17-6
Молекулярная формула:C9H12BFO3
Точка плавления:-
Smiles-код:CC(OC1=C(B(O)O)C(F)=CC=C1)C
Плотность:
Номер в каталоге:CM137244
Молекулярная масса:198
Точка кипения:
Номер Mdl:MFCD06798078
Хранение:

Category Infos

Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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Product Other Information

Product Overview 2-Fluoro-6-isopropoxyphenylboronic acid (2FIPBA) is a boronic acid derivative, first synthesized in 1996 by W. J. Shieh and co-workers. It has been used in a variety of scientific research applications, including as a catalyst in organic synthesis, as a reagent in organometallic chemistry, and in the study of boron-containing compounds.
Synthesis and Application 2-Fluoro-6-isopropoxyphenylboronic acid can be synthesized via a three-step procedure starting from 4-fluoro-3-nitrobenzaldehyde. The first step involves the reaction of 4-fluoro-3-nitrobenzaldehyde with potassium hydroxide and sodium nitrite in ethanol to form 4-fluoro-3-nitrobenzyl alcohol. The second step involves the reaction of 4-fluoro-3-nitrobenzyl alcohol with isopropylmagnesium bromide in THF to form 2-fluoro-6-isopropoxyphenylboronic acid. The final step involves the reaction of 2-fluoro-6-isopropoxyphenylboronic acid with sodium borohydride in THF to form the desired product, 2-Fluoro-6-isopropoxyphenylboronic acid. 2-Fluoro-6-isopropoxyphenylboronic acid has been used in a variety of scientific research applications. It has been used as a catalyst in organic synthesis, as a reagent in organometallic chemistry, and in the study of boron-containing compounds. It has also been used in the synthesis of a variety of compounds, including pyridines, quinolines, and indoles.
Future Directions There are several potential future directions for 2-Fluoro-6-isopropoxyphenylboronic acid. It could be used in the synthesis of novel boron-containing compounds, such as boron-doped semiconductors. It could also be used in the study of boron-containing enzymes and proteins. Additionally, it could be used in the study of boron-containing pharmaceuticals and in the development of new boron-containing drugs. Finally, it could be used in the study of boron-containing materials for use in energy storage and conversion.