Название продукции:Methyl cyclobutanecarboxylate
IUPAC Name:methyl cyclobutanecarboxylate
- CAS:765-85-5
- Молекулярная формула:C6H10O2
- Чистота:95%+
- Номер в каталоге:CM344654
- Молекулярная масса:114.14
Только для использования в НИОКР..
Информация о продукции
- Номер CAS:765-85-5
- Молекулярная формула:C6H10O2
- Точка плавления:-
- Smiles-код:O=C(C1CCC1)OC
- Плотность:
- Номер в каталоге:CM344654
- Молекулярная масса:114.14
- Точка кипения:
- Номер Mdl:MFCD00095142
- Хранение:
Category Infos
- Cyclobutanes
- The molecular structure of cyclobutane has four carbon atoms, and its four carbon atoms are not in the same plane, which is the folded conformation of cyclobutane. Cyclobutane itself is not of commercial or biological interest, but more complex derivatives are important in biology and biotechnology. Currently, nine FDA-approved drugs contain the cyclobutane structure. From the perspective of therapeutic areas, cyclobutyl drugs are mainly distributed in popular areas such as tumors, neurological diseases, infectious diseases, endocrine and metabolic diseases.
Column Infos
- XRD-0394
- XRad Therapeutics announced that the first patient has been dosed in the company’s Phase 1a trial evaluating XRD-0394 in combination with radiation therapy for the treatment of metastatic, locally-advanced or recurrent solid tumors.
XRD-0394, is a first-in-class dual inhibitor of ataxia-telangiectasia mutated (ATM) and DNA-dependent protein kinase (DNA-PK). Initial development efforts are focused on evaluating XRD-0394’s ability to enhance radiation therapy when used in combination. In parallel, the company is exploring the potential benefits of using XRad’s dual kinase inhibitors in combination with targeted radionuclides, immune checkpoint inhibitors, polyadenosine diphosphate-ribose polymerase inhibitors and antibody drug conjugates.