Название продукции:methyl 2,2-difluoro-2-fluorosulfonylacetate

IUPAC Name:methyl 2,2-difluoro-2-(fluorosulfonyl)acetate

CAS:680-15-9
Молекулярная формула:C3H3F3O4S
Чистота:95%
Номер в каталоге:CM333421
Молекулярная масса:192.11

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Информация о продукции

Номер CAS:680-15-9
Молекулярная формула:C3H3F3O4S
Точка плавления:-
Smiles-код:O=C(OC)C(F)(F)S(=O)(F)=O
Плотность:
Номер в каталоге:CM333421
Молекулярная масса:192.11
Точка кипения:
Номер Mdl:MFCD00144316
Хранение:Keep in a tight container and store at 2°C~8°C

Category Infos

Aliphatic Chain Compounds
Aliphatic chain compounds include aliphatic compounds and chain compounds containing other elements or groups. Aliphatic hydrocarbons are hydrocarbons with the basic properties of aliphatic compounds. In aliphatic compounds, carbon atoms are arranged in straight chain, branched chain or cyclic, which are respectively called straight chain aliphatic hydrocarbons, branched chain aliphatic hydrocarbons and alicyclic hydrocarbons. Some cyclic hydrocarbons are different in nature from aromatic hydrocarbons, and are very similar to aliphatic hydrocarbons. Such cyclic hydrocarbons are called alicyclic hydrocarbons. In this way, aliphatic hydrocarbons become a general term for all hydrocarbons except aromatic hydrocarbons. Aliphatic hydrocarbons and their derivatives (including halogenated hydrocarbons) and alicyclic hydrocarbons and their derivatives are collectively referred to as aliphatic compounds.

Column Infos

LTGO-33
Voltage-gated sodium channels (NaVs) are responsible for action potential initiation and transmission of pain signals. NaV1.8 is specifically expressed in peripheral nociceptors and has been genetically and pharmacologically validated as a human pain target.
LTGO-33 inhibited NaV1.8 in the nM potency range and exhibited over 600-fold selectivity against human NaV1.1-NaV1.7 and NaV1.9. Unlike prior reported NaV1.8 inhibitors that preferentially interacted with an inactivated state via the pore region, LTGO-33 was state-independent with similar potencies against closed and inactivated channels.