Название продукции:Cyclopropanecarboxamide

IUPAC Name:cyclopropanecarboxamide

CAS:6228-73-5
Молекулярная формула:C4H7NO
Чистота:95%+
Номер в каталоге:CM202436
Молекулярная масса:85.11

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Информация о продукции

Номер CAS:6228-73-5
Молекулярная формула:C4H7NO
Точка плавления:-
Smiles-код:O=C(C1CC1)N
Плотность:
Номер в каталоге:CM202436
Молекулярная масса:85.11
Точка кипения:248.5°C at 760 mmHg
Номер Mdl:MFCD00013729
Хранение:Store at room temperature.

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.

Column Infos

Deucravacitinib
BMY announced new four-year Sotyktu (deucravacitinib) data demonstrating durable response rates and consistent safety in moderate-to-severe plaque psoriasis. Deucravacitinib is a specific, oral, intracellular TYK2 inhibitor that targets immune responses driven by type 1 IFN and IL-23 that contribute to psoriasis pathogenesis, including IL-17 production and Th1/Th17 polarization.

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