Название продукции:Cyclopropanecarboxamide
IUPAC Name:cyclopropanecarboxamide
- CAS:6228-73-5
- Молекулярная формула:C4H7NO
- Чистота:95%+
- Номер в каталоге:CM202436
- Молекулярная масса:85.11
Только для использования в НИОКР..
Информация о продукции
- Номер CAS:6228-73-5
- Молекулярная формула:C4H7NO
- Точка плавления:-
- Smiles-код:O=C(C1CC1)N
- Плотность:
- Номер в каталоге:CM202436
- Молекулярная масса:85.11
- Точка кипения:248.5°C at 760 mmHg
- Номер Mdl:MFCD00013729
- Хранение:Store at room temperature.
Category Infos
- Cyclopropanes
- Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
Column Infos
- Deucravacitinib
- BMY announced new four-year Sotyktu (deucravacitinib) data demonstrating durable response rates and consistent safety in moderate-to-severe plaque psoriasis. Deucravacitinib is a specific, oral, intracellular TYK2 inhibitor that targets immune responses driven by type 1 IFN and IL-23 that contribute to psoriasis pathogenesis, including IL-17 production and Th1/Th17 polarization.