cas 57260-71-6|| where to buy N-Boc-piperazine

Название продукции:N-Boc-piperazine

IUPAC Name:tert-butyl piperazine-1-carboxylate

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CM103943-500g	in stock	ǙŌ
CM103943-1000g	in stock	ƴŮŮ

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: Номер CAS:57260-71-6; Молекулярная формула:C9H18N2O2; Точка плавления:-; Smiles-код:CC(C)(C)OC(=O)N1CCNCC1; Плотность:

: Номер в каталоге:CM103943; Молекулярная масса:186.26; Точка кипения:; Номер Mdl:MFCD00075265; Хранение:

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: Piperazines; Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.

: Avapritinib; Blueprint Medicines announced the European Commission has approved AYVAKYT® (avapritinib) for the treatment of adult patients with indolent systemic mastocytosis (ISM) with moderate to severe symptoms inadequately controlled on symptomatic treatment. AYVAKYT is the first and only approved therapy for people living with ISM in Europe.  AYVAKYT was designed to potently and selectively target KIT D816V, the primary underlying driver of the disease.
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: Saruparib; Saruparib, a selective inhibitor of poly-ADP ribose polymerase 1 (PARP1), demonstrated a promising objective response rate and progression-free survival in patients with certain homologous recombination repair (HRR)-deficient breast cancers, according to results from the phase I/II PETRA trial presented at the American Association for Cancer Research (AACR) Annual Meeting 2024.
Saruparib, a PARP1-specific inhibitor, showed promising tumor growth inhibition in preclinical models of breast, ovarian, pancreatic, and prostate cancer harboring HRR deficiency mutations. Because saruparib was less toxic than other PARP inhibitors, it could be given at higher doses.