Название продукции:1,4,8-Triazaspiro[5.5]undecane

IUPAC Name:1,4,8-triazaspiro[5.5]undecane

CAS:554435-42-6
Молекулярная формула:C8H17N3
Чистота:97%
Номер в каталоге:CM215005
Молекулярная масса:155.25

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Информация о продукции

Номер CAS:554435-42-6
Молекулярная формула:C8H17N3
Точка плавления:-
Smiles-код:N1CCNCC12CNCCC2
Плотность:
Номер в каталоге:CM215005
Молекулярная масса:155.25
Точка кипения:
Номер Mdl:
Хранение:

Category Infos

Piperidines
Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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Piperazines
Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
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