cas 53053-08-0|| where to buy N3-Ph-NHS ester

Название продукции:N3-Ph-NHS ester

IUPAC Name:2,5-dioxopyrrolidin-1-yl 4-azidobenzoate

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CM339184-100mg	in stock	ňƩƩ

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: Номер CAS:53053-08-0; Молекулярная формула:C11H8N4O4; Точка плавления:-; Smiles-код:O=C(ON1C(CCC1=O)=O)C2=CC=C(N=[N+]=[N-])C=C2; Плотность:

: Номер в каталоге:CM339184; Молекулярная масса:260.21; Точка кипения:; Номер Mdl:; Хранение:

: ADC-Linkers; The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.

: Azides; Azides are used in click chemistry, such as copper-catalyzed azide-alkyne [3+2] cycloaddition (CuAAC),and strain-promoted [3+2] azide-alkyne cycloaddition reaction (SPAAC).

: Non-cleavable linkers; Noncleavable linkers consist of stable bonds that resist proteolytic degradation and provide higher stability than the cleavable linkers.