Название продукции:Ethyl 3-oxopentanoate

IUPAC Name:ethyl 3-oxopentanoate

CAS:4949-44-4
Молекулярная формула:C7H12O3
Чистота:98%
Номер в каталоге:CM253179
Молекулярная масса:144.17

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Информация о продукции

Номер CAS:4949-44-4
Молекулярная формула:C7H12O3
Точка плавления:-
Smiles-код:CCC(CC(OCC)=O)=O
Плотность:
Номер в каталоге:CM253179
Молекулярная масса:144.17
Точка кипения:193°C at 760 mmHg
Номер Mdl:MFCD00009317
Хранение:Keep in a tight container and store at ambient temperature,protect from light

Column Infos

VX-548
Vertex announced positive results from its Phase 2 dose-ranging study of VX-548 in people with painful diabetic peripheral neuropathy (DPN). VX-548 is an investigational oral, selective NaV1.8 inhibitor that is highly selective for NaV1.8 relative to other NaV channels. NaV1.8 is a voltage-gated sodium channel that plays a critical role in pain signaling in the peripheral nervous system. NaV1.8 is a genetically validated target for the treatment of pain. Vertex's strategy is to develop new drug types by selectively inhibiting NaV1.8. Compared to opioid drugs, they may provide better analgesic effects while avoiding side effects such as addiction. VX-548 has been granted Breakthrough Therapy and Fast Track designations in the U.S. for moderate to severe acute pain.