Название продукции:4-Chloro-2-methoxy-1-methylbenzene

IUPAC Name:4-chloro-2-methoxy-1-methylbenzene

CAS:40794-04-5
Молекулярная формула:C8H9ClO
Чистота:97%
Номер в каталоге:CM283380
Молекулярная масса:156.61

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Информация о продукции

Номер CAS:40794-04-5
Молекулярная формула:C8H9ClO
Точка плавления:-
Smiles-код:CC1=CC=C(Cl)C=C1OC
Плотность:
Номер в каталоге:CM283380
Молекулярная масса:156.61
Точка кипения:204°C at 760 mmHg
Номер Mdl:MFCD07368289
Хранение:Store at 2-8°C.

Column Infos

Crinecerfont
The New England Journal of Medicine publishes the primary CAHtalyst™ Adult Phase 3 study results of Crinecerfont for the treatment of congenital adrenal hyperplasia (CAH). Classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) is a rare genetic disorder, affected by a lack of cortisol and/or aldosterone. Corticotropin-releasing factor type 1 receptor (CRF1) antagonism is shown to clinically decrease ACTH production and adrenal androgen levels.
Neurocrine's Crinecerfont is an investigational, selective CRF1 antagonist being developed to reduce and control excess adrenocorticotropic hormone (ACTH) and adrenal androgens. The phase 3 study meets primary and important key secondary endpoints, including a significant reduction in androstenedione levels and lowering glucocorticoid dosing.