Название продукции:Methyl (S)-hexahydropyridazine-3-carboxylate hydrochloride
IUPAC Name:methyl (3S)-1,2-diazinane-3-carboxylate hydrochloride
- CAS:380223-17-6
- Молекулярная формула:C6H13ClN2O2
- Чистота:95%+
- Номер в каталоге:CM560583
- Молекулярная масса:180.63
Только для использования в НИОКР..
Информация о продукции
- Номер CAS:380223-17-6
- Молекулярная формула:C6H13ClN2O2
- Точка плавления:-
- Smiles-код:O=C([C@@H]1CCCNN1)OC.Cl
- Плотность:
- Номер в каталоге:CM560583
- Молекулярная масса:180.63
- Точка кипения:
- Номер Mdl:
- Хранение:
Column Infos
- RMC-6236
- Over 30% of all human cancers, including a certain percentage of pancreatic, colorectal, lung cancers, and AML are driven by mutations of RAS genes. There is a significant unmet medical need in RAS mutant cancers.
Revolution Medicines’ investigational drug, RMC-6236 is an oral, non-covalent, RAS (ON) inhibitor that is selective for the active, GTP-bound state of both mutant and wild-type variants of the canonical RAS isoforms. RMC-6236 is under clinical phase I studies as monotherapy in NSCLC and PDAC, and advanced solid tumors harboring KRAS G12X mutations.