Название продукции:Potassium thiocyanate
- CAS:333-20-0
- Молекулярная формула:CKNS
- Чистота:98%
- Номер в каталоге:CM000375
- Молекулярная масса:97.18
Только для использования в НИОКР..
Информация о продукции
- Номер CAS:333-20-0
- Молекулярная формула:CKNS
- Точка плавления:-
- Smiles-код:[S-]C#N.[K+]
- Плотность:
- Номер в каталоге:CM000375
- Молекулярная масса:97.18
- Точка кипения:
- Номер Mdl:MFCD00011413
- Хранение:
Column Infos
- Crinecerfont
- The New England Journal of Medicine publishes the primary CAHtalyst™ Adult Phase 3 study results of Crinecerfont for the treatment of congenital adrenal hyperplasia (CAH). Classic congenital adrenal hyperplasia (CAH) due to 21-hydroxylase deficiency (21OHD) is a rare genetic disorder, affected by a lack of cortisol and/or aldosterone. Corticotropin-releasing factor type 1 receptor (CRF1) antagonism is shown to clinically decrease ACTH production and adrenal androgen levels.
Neurocrine's Crinecerfont is an investigational, selective CRF1 antagonist being developed to reduce and control excess adrenocorticotropic hormone (ACTH) and adrenal androgens. The phase 3 study meets primary and important key secondary endpoints, including a significant reduction in androstenedione levels and lowering glucocorticoid dosing.