Название продукции:tert-butyl 4-(1-methoxy-1,3-dioxopentan-2-yl)piperazine-1-carboxylate
IUPAC Name:tert-butyl 4-(1-methoxy-1,3-dioxopentan-2-yl)piperazine-1-carboxylate
- CAS:2869955-99-5
- Молекулярная формула:C15H26N2O5
- Чистота:95%+
- Номер в каталоге:CM1078120
- Молекулярная масса:314.38
Только для использования в НИОКР..
Информация о продукции
- Номер CAS:2869955-99-5
- Молекулярная формула:C15H26N2O5
- Точка плавления:-
- Smiles-код:O=C(OC(C)(C)C)N1CCN(CC1)C(C(=O)OC)C(=O)CC
- Плотность:1.130±0.06 g/cm3
- Номер в каталоге:CM1078120
- Молекулярная масса:314.38
- Точка кипения:397.8±42.0 °C
- Номер Mdl:
- Хранение:
Category Infos
- Piperazines
- Piperazine is an organic compound consisting of a six-membered ring containing two nitrogen atoms in opposite positions in the ring. The chemical formula of piperazine is C4H10N2, and it is an important pharmaceutical intermediate. Pyrimidines and piperazines are known to be the backbone of many bulk compounds and important core structures for approved drugs; studies have shown that combining a pyridine ring with a piperazine moiety within a single structural framework enhances biological activity.
Column Infos
- HRO761
- Novartis'HRO761 is an oral allosteric inhibitor targeting WRN helicase, aimed at treating microsatellite instability (MSI) or deficient mismatch repair (dMMR) tumors. WRN has emerged as a critical synthetic lethal target in MSI cancers, which are common in colorectal, gastric, endometrial, and ovarian cancers. Although MSI cancers show a high response rate to immune checkpoint inhibitors, many patients develop resistance. By acting on WRN, HRO761 may be able to stop the growth of the cancer.
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