Название продукции:1,2,5-Oxadiazole-3-carboxamide, N-[(S)-(4,4-difluorocyclohexyl)[7-[(1S)-2-methoxy-1-[(4S)-2-oxo-4-(trifluoromethyl)-1-imidazolidinyl]ethyl]imidazo[1,2-b]pyridazin-2-yl]methyl]-4-methyl-

IUPAC Name:N-[(S)-(4,4-difluorocyclohexyl)({7-[(1S)-2-methoxy-1-[(4S)-2-oxo-4-(trifluoromethyl)imidazolidin-1-yl]ethyl]imidazo[1,2-b]pyridazin-2-yl})methyl]-4-methyl-1,2,5-oxadiazole-3-carboxamide

CAS:2452464-73-0
Молекулярная формула:C24H27F5N8O4
Чистота:98%
Номер в каталоге:CM545836
Молекулярная масса:586.52

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Информация о продукции

Номер CAS:2452464-73-0
Молекулярная формула:C24H27F5N8O4
Точка плавления:-
Smiles-код:COC[C@@H](N1C[C@H](NC1=O)C(F)(F)F)C1=CC2=NC(=CN2N=C1)[C@@H](NC(=O)C1=NON=C1C)C1CCC(F)(F)CC1
Плотность:
Номер в каталоге:CM545836
Молекулярная масса:586.52
Точка кипения:
Номер Mdl:
Хранение:

Category Infos

Imidazopyridazines
Potent IRAK-4 inhibitors have been reported by several groups including some structurally related benzimidazoles as well as alternative fused heterocycles such as the imidazopyridine and imidazopyridazine. Such compounds are reported to have IRAK-1 and IRAK-4 activity with varying degrees of selectivity.
Furazans
Incorporation of heterocycles into drug molecules can enhance physical properties and biological activity. Oxadiazoles are a class of five-membered heterocycles containing one oxygen and two nitrogen atoms with special biological activity and thermodynamic properties. 1,2,4- and 1,3,4-oxadiazoles are widely used in the development of bioactive molecules, but 1,2,5-oxadiazoles (furazans) are used relatively sparingly. Compared with 1,2,4- and 1,3,4-isomers, 1,2,5-oxadiazole has unique physicochemical properties and electronic effects. The furazan ring has a strong inductive effect, comparable to that of trifluoromethyl or tetrazolyl. The unique properties of furoxan can confer specific pharmacological activities to drug-like molecules.