Название продукции:3-[5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl]propanoic acid

IUPAC Name:3-[5,7-difluoro-2-(4-fluorophenyl)-1H-indol-3-yl]propanoic acid

CAS:2446818-55-7
Молекулярная формула:C17H12F3NO2
Чистота:95%+
Номер в каталоге:CM1075856
Молекулярная масса:319.28

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Информация о продукции

Номер CAS:2446818-55-7
Молекулярная формула:C17H12F3NO2
Точка плавления:-
Smiles-код:C1=CC(=CC=C1C2=C(C3=C(N2)C(=CC(=C3)F)F)CCC(=O)O)F
Плотность:
Номер в каталоге:CM1075856
Молекулярная масса:319.28
Точка кипения:
Номер Mdl:
Хранение:

Category Infos

Indoles
Indole is a compound of pyrrole and benzene in parallel, also known as benzopyrrole. There are two combinations of pyrrole and benzene, called indole and isoindole, respectively. Many derivatives of indole have physiological and pharmacological activities, and can synthesize vasodilators, antihistamines, antipyretic analgesics, etc. in medicine, so indole is also a very important heterocyclic compound.
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Column Infos

VX-147
Vertex Pharmaceuticals announced that inaxaplin (VX-147) , a first-in-class molecule has advanced into the Phase 3 portion of the global Phase 2/3 pivotal clinical trial in APOL1-mediated kidney disease (AMKD), where a 45 mg once daily oral dose will be compared to placebo, on top of standard of care. The clinical trial is designed to assess the impact of inaxaplin on kidney function and proteinuria for people living with proteinuric kidney disease mediated by two variants in the APOL1 gene, known as AMKD. In addition, the trial has been expanded to include adolescents with AMKD ages 10 to 17 years.
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