Название продукции:dimethyl({[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl})amine

IUPAC Name:dimethyl({[3-methyl-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]methyl})amine

CAS:2369772-15-4
Молекулярная формула:C16H26BNO2
Чистота:95%+
Номер в каталоге:CM1077583
Молекулярная масса:275.2

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Информация о продукции

Номер CAS:2369772-15-4
Молекулярная формула:C16H26BNO2
Точка плавления:-
Smiles-код:CN(C)CC1=CC=C(B2OC(C)(C)C(C)(C)O2)C(C)=C1
Плотность:
Номер в каталоге:CM1077583
Молекулярная масса:275.2
Точка кипения:
Номер Mdl:
Хранение:

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Boronic Acids and Esters
Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).
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ORIC-944
ORIC-944 is a potent and selective allosteric inhibitor of PRC2 developed by ORIC Pharmaceuticals. Initiated dosing of ORIC-944 in combination with NUBEQA® (darolutamide) and in combination with ERLEADA® (apalutamide) in the ongoing Phase 1b trial for prostate cancer in first half of 2024. Entered into clinical trial collaboration and supply agreements with Bayer and Johnson & Johnson to support the ongoing Phase 1b trial of ORIC-944 in combinations with AR inhibitors for the treatment of prostate cancer.
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