Название продукции:(3S,4R)-3-amino-4-hydroxy-pyrrolidin-2-one
IUPAC Name:(3S,4R)-3-amino-4-hydroxypyrrolidin-2-one
- CAS:220812-09-9
- Молекулярная формула:C4H8N2O2
- Чистота:95%+
- Номер в каталоге:CM1018618
- Молекулярная масса:116.12
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Информация о продукции
- Номер CAS:220812-09-9
- Молекулярная формула:C4H8N2O2
- Точка плавления:-
- Smiles-код:N[C@@H]1C(=O)NC[C@H]1O
- Плотность:
- Номер в каталоге:CM1018618
- Молекулярная масса:116.12
- Точка кипения:
- Номер Mdl:
- Хранение:
Category Infos
- Pyrrolidines
- Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Column Infos
- VX-147
- Vertex Pharmaceuticals announced that inaxaplin (VX-147) , a first-in-class molecule has advanced into the Phase 3 portion of the global Phase 2/3 pivotal clinical trial in APOL1-mediated kidney disease (AMKD), where a 45 mg once daily oral dose will be compared to placebo, on top of standard of care. The clinical trial is designed to assess the impact of inaxaplin on kidney function and proteinuria for people living with proteinuric kidney disease mediated by two variants in the APOL1 gene, known as AMKD. In addition, the trial has been expanded to include adolescents with AMKD ages 10 to 17 years.
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