Название продукции:3-[5-(5-aminopent-1-ynyl)-1-oxo-isoindolin-2-yl]piperidine-2,6-dione
IUPAC Name:3-[5-(5-aminopent-1-yn-1-yl)-1-oxo-2,3-dihydro-1H-isoindol-2-yl]piperidine-2,6-dione
- CAS:2138440-56-7
- Молекулярная формула:C18H19N3O3
- Чистота:95%
- Номер в каталоге:CM1077233
- Молекулярная масса:325.37
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Информация о продукции
- Номер CAS:2138440-56-7
- Молекулярная формула:C18H19N3O3
- Точка плавления:-
- Smiles-код:NCCCC#CC1=CC=C2C(CN(C3CCC(=O)NC3=O)C2=O)=C1
- Плотность:
- Номер в каталоге:CM1077233
- Молекулярная масса:325.37
- Точка кипения:
- Номер Mdl:
- Хранение:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.