Название продукции:(2S,4R)-1-[(2S)-3,3-dimethyl-2-[(2-prop-2-ynoxyacetyl)amino]butanoyl]-4-hydroxy-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide
IUPAC Name:(2S,4R)-1-[(2S)-3,3-dimethyl-2-[2-(prop-2-yn-1-yloxy)acetamido]butanoyl]-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}pyrrolidine-2-carboxamide
- CAS:2098799-78-9
- Молекулярная формула:C27H34N4O5S
- Чистота:95%+
- Номер в каталоге:CM340798
- Молекулярная масса:526.65
Только для использования в НИОКР..
Информация о продукции
- Номер CAS:2098799-78-9
- Молекулярная формула:C27H34N4O5S
- Точка плавления:-
- Smiles-код:O=C([C@H]1N(C([C@@H](NC(COCC#C)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2
- Плотность:
- Номер в каталоге:CM340798
- Молекулярная масса:526.65
- Точка кипения:
- Номер Mdl:
- Хранение:
Category Infos
- PROTAC-E3 Ligase Ligands
- Bifunctional degrader molecules, also called proteolysis-targeting chimeras (PROTACs), are a new modality of chemical tools and potential therapeutics to understand and treat human disease. A required PROTAC component is a ligand binding to an E3 ubiquitin ligase, which is then joined to another ligand binding to a protein to be degraded via the ubiquitin–proteasome system. The advent of nonpeptidic small-molecule E3 ligase ligands revolutionized the field and ushered in the design of drug-like PROTACs with potent and selective degradation activity.
- PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- Proteolysis-Targeting Chimeras | PROTAC-E3 Ligase Ligands | PROTACs | Bifunctional Degrader Molecules
- PROTAC (Proteolysis-Targeting Chimeras) is a promising approach in drug discovery that involves the use of small molecules to target specific proteins for degradation by the cellular machinery.