cas 2098215-73-5|| where to buy [4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methanamine

Название продукции:[4-[1-methyl-4-(trifluoromethyl)imidazol-2-yl]phenyl]methanamine

IUPAC Name:1-{4-[1-methyl-4-(trifluoromethyl)-1H-imidazol-2-yl]phenyl}methanamine

: CAS：2098215-73-5; Молекулярная формула：C12H12F3N3; Чистота：95%+

: Номер в каталоге：CM1017820; Молекулярная масса：255.24

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Информация о продукции

: Номер CAS:2098215-73-5; Молекулярная формула:C12H12F3N3; Точка плавления:-; Smiles-код:NCC1=CC=C(C=C1)C2N(C)C=C(C(F)(F)F)N=2; Плотность:

: Номер в каталоге:CM1017820; Молекулярная масса:255.24; Точка кипения:; Номер Mdl:; Хранение:

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: Fluorinated Compounds; Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.

Column Infos

: TNG348; Dose escalation is ongoing in the TNG348, a novel inhibitor of USP1 (ubiquitin-specific protease 1), phase 1/2 clinical trial evaluating the safety, pharmacokinetics, pharmacodynamics and efficacy of TNG348 as a single agent and in combination with olaparib, a PARP inhibitor, in patients with BRCA1/2 mutant and other HRD+ (homologous recombination deficient) cancers. The first patient dosed was announced in January 2024.Chemenu has been working to develop more compounds for drug discovery. Here are the building blocks we can provide.

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