Название продукции:(3S,4S)-1-(1H-1,3-benzodiazol-2-yl)-4-(trifluoromethyl)pyrrolidine-3-carboxamide

IUPAC Name:(3S,4S)-1-(1H-1,3-benzodiazol-2-yl)-4-(trifluoromethyl)pyrrolidine-3-carboxamide

CAS:1938818-70-2
Молекулярная формула:C13H13F3N4O
Чистота:95%+
Номер в каталоге:CM1030085
Молекулярная масса:298.27

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Информация о продукции

Номер CAS:1938818-70-2
Молекулярная формула:C13H13F3N4O
Точка плавления:-
Smiles-код:NC(=O)[C@@H]1CN(C[C@H]1C(F)(F)F)C1=NC2=CC=CC=C2N1
Плотность:
Номер в каталоге:CM1030085
Молекулярная масса:298.27
Точка кипения:
Номер Mdl:
Хранение:

Category Infos

Fluorinated Compounds
Fluorine is the most electronegative element in the periodic table, and the fluorine atom has a small atomic radius, so fluorine-containing organic compounds have many wonderful properties. For example, the introduction of fluorine atoms or fluorine-containing groups into drug molecules can improve the permeability to cell membranes, metabolic stability and bioavailability; in addition, the introduction of fluorine atoms will improve the lipid solubility of the compound and promote its absorption in the body. The speed of delivery changes the physiological effect. In the field of medicinal chemistry, the introduction of fluorine atoms into organic molecules is an important direction for the development of new anticancer drugs, antitumor drugs, antiviral agents, anti-inflammatory drugs, and central nervous system drugs.
Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.
Benzimidazoles
Benzimidazole is a benzo derivative of imidazole. It is a kind of bicyclic aromatic organic compounds, which is formed by fusing a six-membered benzene ring and five-membered imidazole at positions 4 and 5 of imidazole ring. It is an important pharmacophore of many biologically active heterocyclic compounds with various pharmacological activities. Benzimidazoles and their derivatives have developed into dynamic heterocyclic systems due to their potency in a variety of biologically active compounds such as anticancer, bactericidal and antiviral drugs. Benzimidazoles are a class of therapeutic motifs with broad relevance in medicinal chemistry.

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