Название продукции:3,6-dichloro-4-(3-methyloxetan-3-yl)pyridazine
IUPAC Name:3,6-dichloro-4-(3-methyloxetan-3-yl)pyridazine
- CAS：1887223-11-1
- Молекулярная формула：C8H8Cl2N2O
- Чистота：95%+
- Номер в каталоге：CM388403
- Молекулярная масса：219.07
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Информация о продукции
- Номер CAS:1887223-11-1
- Молекулярная формула:C8H8Cl2N2O
- Точка плавления:-
- Smiles-код:CC1(COC1)C1=CC(Cl)=NN=C1Cl
- Плотность:
- Номер в каталоге:CM388403
- Молекулярная масса:219.07
- Точка кипения:
- Номер Mdl:
- Хранение:
Category Infos
- Pyridazines
- Pyridazine, also known as o-diazobenzene, is a six-membered heterocyclic compound containing two nitrogen heteroatoms in the 1 and 2 positions with a special structure and a wide biological activity. Pyridazine is more and more popular in drug development, and a variety of pyridazine drugs have been developed and marketed. From the perspective of the therapeutic field, pyridazine drug molecules are mainly used for tumor treatment, but also involve in many therapeutic fields such as inflammation, hypertension and cardiovascular disease. With the increase and in-depth of research, pyridazine drugs will play more roles in the treatment of diseases.
- Oxetanes
- Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.
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