cas 1820747-66-7|| where to buy 2-(oxetan-3-yl)cyclohexan-1-one

Название продукции:2-(oxetan-3-yl)cyclohexan-1-one

IUPAC Name:2-(oxetan-3-yl)cyclohexan-1-one

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: Номер CAS:1820747-66-7; Молекулярная формула:C9H14O2; Точка плавления:-; Smiles-код:O=C1C(C2COC2)CCCC1; Плотность:

: Номер в каталоге:CM327610; Молекулярная масса:154.21; Точка кипения:; Номер Mdl:; Хранение:

: Cyclohexanes; Cyclohexane is an organic compound with a chemical formula C6H12. It is a colorless liquid with a pungent odor, insoluble in water, and soluble in most organic solvents such as ethanol, ether, benzene, and acetone. Cyclohexyl fragments are a common structure in both natural and synthetic drugs. It can be used as both core structure and part of achiral side chain.

: Oxetanes; Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.