Название продукции:Bis-sulfone-PEG3-Azide

IUPAC Name:N-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl)-4-[3-(4-methylbenzenesulfonyl)-2-[(4-methylbenzenesulfonyl)methyl]propanoyl]benzamide

CAS:1802908-01-5
Молекулярная формула:C33H40N4O9S2
Чистота:95%+
Номер в каталоге:CM339146
Молекулярная масса:700.82

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Информация о продукции

Номер CAS:1802908-01-5
Молекулярная формула:C33H40N4O9S2
Точка плавления:-
Smiles-код:O=C(NCCOCCOCCOCCN=[N+]=[N-])C1=CC=C(C(C(CS(=O)(C2=CC=C(C)C=C2)=O)CS(=O)(C3=CC=C(C)C=C3)=O)=O)C=C1
Плотность:
Номер в каталоге:CM339146
Молекулярная масса:700.82
Точка кипения:
Номер Mdl:
Хранение:

Category Infos

ADC-Linkers
The ADC linker is one of the three main components of antibody drug conjugates (ADCs), linking the antibody to the effective drug (payload) through chemical bonds. ADC linkers play a key role in determining the overall success of antibody drug conjugates. One of the major challenges in developing safe and effective ADC drugs is to assemble an ideal chemical linker between the cytotoxic payload and the mAb. Well-designed ADC linkers can help the selective delivery of antibodies at the tumor site and the accurate release of cytotoxic drugs.
Cleavable linkers
Cleavable linkers rely on the inherent properties of a cell’s cytoplasmic compartments for selective release of the cytotoxic drug.
PEG linkers
PEG Reagents are chemically functionalized polyethylene glycol (PEG) linkers.PEG linkers are highly water-soluble and non-immunogenic linkers.
Azides
Azides are used in click chemistry, such as copper-catalyzed azide-alkyne [3+2] cycloaddition (CuAAC),and strain-promoted [3+2] azide-alkyne cycloaddition reaction (SPAAC).