cas 1781577-31-8|| where to buy 1-(6-chloropyridazin-3-yl)cyclopropan-1-amine

Название продукции:1-(6-chloropyridazin-3-yl)cyclopropan-1-amine

IUPAC Name:1-(6-chloropyridazin-3-yl)cyclopropan-1-amine

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: Номер CAS:1781577-31-8; Молекулярная формула:C7H8ClN3; Точка плавления:-; Smiles-код:C1CC1(C2=NN=C(C=C2)Cl)N; Плотность:

: Номер в каталоге:CM1046741; Молекулярная масса:169.61; Точка кипения:; Номер Mdl:; Хранение:

: Pyridazines; Pyridazine, also known as o-diazobenzene, is a six-membered heterocyclic compound containing two nitrogen heteroatoms in the 1 and 2 positions with a special structure and a wide biological activity. Pyridazine is more and more popular in drug development, and a variety of pyridazine drugs have been developed and marketed. From the perspective of the therapeutic field, pyridazine drug molecules are mainly used for tumor treatment, but also involve in many therapeutic fields such as inflammation, hypertension and cardiovascular disease. With the increase and in-depth of research, pyridazine drugs will play more roles in the treatment of diseases.

: Cyclopropanes; Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.