cas 1739-60-2|| where to buy 4-chloro-5-methoxy-6-methylpyrimidine

Название продукции:4-chloro-5-methoxy-6-methylpyrimidine

IUPAC Name:4-chloro-5-methoxy-6-methylpyrimidine

Упаковочная единица	Доступно для заказа	Цена ($)	Количество
CM407847-1g	1-2 Weeks	ſǲƻ

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: Номер CAS:1739-60-2; Молекулярная формула:C6H7ClN2O; Точка плавления:-; Smiles-код:COC1=C(Cl)N=CN=C1C; Плотность:

: Номер в каталоге:CM407847; Молекулярная масса:158.59; Точка кипения:; Номер Mdl:; Хранение:

: Pyrimidines; Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.

: HRO761; Novartis'HRO761 is an oral allosteric inhibitor targeting WRN helicase, aimed at treating microsatellite instability (MSI) or deficient mismatch repair (dMMR) tumors. WRN has emerged as a critical synthetic lethal target in MSI cancers, which are common in colorectal, gastric, endometrial, and ovarian cancers. Although MSI cancers show a high response rate to immune checkpoint inhibitors, many patients develop resistance. By acting on WRN, HRO761 may be able to stop the growth of the cancer.
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