Название продукции:4-(2-Chloro-6-((1-(cyclopropylmethyl)piperidin-4-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine
IUPAC Name:4-(2-chloro-6-{[1-(cyclopropylmethyl)piperidin-4-yl]methyl}thieno[3,2-d]pyrimidin-4-yl)morpholine
- CAS:1439824-03-9
- Молекулярная формула:C20H27ClN4OS
- Чистота:95%
- Номер в каталоге:CM151530
- Молекулярная масса:406.97
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Информация о продукции
- Номер CAS:1439824-03-9
- Молекулярная формула:C20H27ClN4OS
- Точка плавления:-
- Smiles-код:ClC1=NC(N2CCOCC2)=C3C(C=C(CC4CCN(CC5CC5)CC4)S3)=N1
- Плотность:
- Номер в каталоге:CM151530
- Молекулярная масса:406.97
- Точка кипения:
- Номер Mdl:MFCD22690802
- Хранение:
Category Infos
- Piperidines
- Piperidine is an azacycloalkane that is cyclohexane in which one of the carbons is replaced by a nitrogen. Although piperidine is a common organic compound, it is an immensely important class of compounds medicinally: the piperidine ring is the most common heterocyclic subunit among FDA approved drugs.
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- Morpholines
- Morpholine contains secondary amine groups and has all the typical reactive characteristics of secondary amine groups. It can react with inorganic acids to form salts, and react with organic acids to form salts or amides, which can be subjected to alkylation reaction, and can also be reacted with ethylene oxide, ketone or Willgerodt reaction. Morpholine is a six-membered ring containing oxygen and nitrogen, and its alkalinity is much lower than that of its parent piperidine. The marketed morpholine drugs are mainly distributed in the fields of tumors, cardiovascular and cerebrovascular diseases, respiratory system diseases, digestive system diseases, infectious diseases and mental disorders.
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- Thienopyrimidines
- Thienopyrimidines are a class of heterocyclic compounds with diverse biological activities depending on their detailed substitution patterns. In addition, many thienopyrimidine derivatives have shown potent activity against cancer cell lines and specific oncogenes.
- Cyclopropanes
- Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.