Название продукции:(2-(Azetidin-1-yl)pyrimidin-5-yl)boronic acid
IUPAC Name:[2-(azetidin-1-yl)pyrimidin-5-yl]boronic acid
- CAS:1411643-59-8
- Молекулярная формула:C7H10BN3O2
- Чистота:95%+
- Номер в каталоге:CM135138
- Молекулярная масса:178.98
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Информация о продукции
- Номер CAS:1411643-59-8
- Молекулярная формула:C7H10BN3O2
- Точка плавления:-
- Smiles-код:OB(C1=CN=C(N2CCC2)N=C1)O
- Плотность:
- Номер в каталоге:CM135138
- Молекулярная масса:178.98
- Точка кипения:
- Номер Mdl:MFCD18261197
- Хранение:
Category Infos
- Pyrimidines
- Pyrimidine, also known as 1,3-diazobenzene, is a heterocyclic compound with the chemical formula C4H4N2. Pyrimidine is formed by substituting 2 nitrogen atoms for 2 carbons in the meta-position of benzene. It is a diazine and retains its aromaticity. Derivatives of pyrimidine widely exist in organic macromolecular nucleic acids, and many drugs also contain pyrimidine rings. In nucleic acids, three nucleobases are pyrimidine derivatives: cytosine, thymine and uracil. There are a variety of pyrimidine-containing drugs on the market, most of which are kinase inhibitors.
- Azetidines
- Azetidines are an important class of saturated four-membered nitrogen-containing heterocyclic compounds. The research hotspots related to this structure mainly focus on two aspects: one is the research of pharmaceutical chemistry; the other is related to chiral azetidines, using rigid azetidine compounds as chiral ligands for asymmetric catalytic reactions. Many nitrogen-containing heterocycles play important roles in drug structures, and in many cases small structural changes can improve ligand selectivity and pharmacokinetic properties.
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Column Infos
- Boronic Acids and Esters
- Boronic acids and boronate esters are commonly used reagents in Suzuki–Miyaura coupling chemistry. Organoboron derivatives are common reagents for C–C bond formation, either through classical palladium-mediated transformations or through other newer coupling methods. Boronic esters and acids are potential intermediates in the manufacture of many active pharmaceutical ingredients (API).