Compared to quinolines, isoquinolines are also prominent structural motifs present in many biologically significant natural and synthetic compounds. Some well-known isoquinoline alkaloids include the anticancer and anticonvulsant berberine, the vasodilator and antispasmodic drugs papaverine and emetine. In addition to naturally occurring isoquinolines, synthetic analogs have also shown significant biological activity.
Benzoxazines are a type of heterocyclic compounds consisting of benzene and oxazine rings. Benzoxazine research is developing rapidly because of the many potential applications of the materials.
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