Название продукции:tert-Butyl azepane-1-carboxylate
IUPAC Name:tert-butyl azepane-1-carboxylate
- CAS:123387-52-0
- Молекулярная формула:C11H21NO2
- Чистота:95%
- Номер в каталоге:CM284811
- Молекулярная масса:199.29
Только для использования в НИОКР..
Информация о продукции
- Номер CAS:123387-52-0
- Молекулярная формула:C11H21NO2
- Точка плавления:-
- Smiles-код:O=C(N1CCCCCC1)OC(C)(C)C
- Плотность:
- Номер в каталоге:CM284811
- Молекулярная масса:199.29
- Точка кипения:
- Номер Mdl:MFCD18252672
- Хранение:
Category Infos
- Azepanes
- The use of azepane as a scaffold for drug discovery remains of interest. The azepane linker is the key to efficient activity. A number of seven-membered ring derivatives have been prepared or investigated for their potential or actual pharmacological properties. Examples include azaalkane derivatives as PKB (protein kinase B) inhibitors.
Column Infos
- Taplucainium chloride
- Nocion Therapeutics presents data on preclinical and clinical development of Taplucainium, a novel, charged sodium channel blocker, as a potential treatment for chronic cough at the 13th London International Cough Symposium.
Taplucainium is a proprietary molecule in the novel class of charged sodium channel blockers that allows for specific silencing of activated/inflamed nociceptors while having minimal local off-target effects or systemic exposure. Unlike other investigative cough therapies, such as P2X3-antagonists, TRPA1-antagonists and TRPM8-agonists, which target a specific large pore channel, taplucainium works downstream by selectively targeting the sodium channels in activated nociceptors which are the target of these large pore channels.