Название продукции:5-Fluoro-2,3-dihydrospiro[indene-1,2'-pyrrolidine]

IUPAC Name:5-fluoro-2,3-dihydrospiro[indene-1,2'-pyrrolidine]

CAS:1211594-23-8
Молекулярная формула:C12H14FN
Чистота:95%
Номер в каталоге:CM139314
Молекулярная масса:191.25

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Информация о продукции

Номер CAS:1211594-23-8
Молекулярная формула:C12H14FN
Точка плавления:-
Smiles-код:FC1=CC2=C(C3(NCCC3)CC2)C=C1
Плотность:
Номер в каталоге:CM139314
Молекулярная масса:191.25
Точка кипения:
Номер Mdl:MFCD11616031
Хранение:Store at 2-8°C.

Category Infos

Spiro Compounds
A spiro compound is a polycyclic compound in which two monocyclic rings share one carbon atom; the shared carbon atom is called a spiro atom. Spiro compounds have rigid structures, stable structures, and have special properties that general organic compounds do not possess, such as anomeric effect, spiro conjugation and spiro hyperconjugation. Compared with the monocyclic structure or the planar aromatic structure, the spiro structure has a larger three-dimensional structure; the heterocyclic spiro structure is also regarded as the biological isostere of some groups, which can change the drug to a certain extent. The water solubility, lipophilicity, dominant conformation and ADMET properties of the molecule make the optimized lead molecule easier to drug. Therefore, spiro compounds occupy a very important position in drug development.
Spiro And Bicyclic Compound
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Pyrrolidines
Pyrrolidine, also known as tetrahydropyrrole, is a saturated five-membered heterocyclic ring, which is miscible with water. Pyrrolidine exists in many alkaloids and drug molecules, such as kappa opioids, antagonists of dopamine D4 receptors, and HIV reverse transcriptase inhibitors.