Название продукции:(4-(1-methyl-1H-pyrazol-4-yl)phenyl)methanamine

IUPAC Name:1-[4-(1-methyl-1H-pyrazol-4-yl)phenyl]methanamine

CAS:1184589-25-0
Молекулярная формула:C11H13N3
Чистота:95%+
Номер в каталоге:CM362822
Молекулярная масса:187.25

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Информация о продукции

Номер CAS:1184589-25-0
Молекулярная формула:C11H13N3
Точка плавления:-
Smiles-код:CN1C=C(C=N1)C1=CC=C(CN)C=C1
Плотность:
Номер в каталоге:CM362822
Молекулярная масса:187.25
Точка кипения:
Номер Mdl:
Хранение:

Category Infos

Pyrazoles
Pyrazoles are organic compounds of the general formula C3H3N2H. It is a five-membered heterocycle consisting of three carbon atoms and two adjacent nitrogen atoms. As an H-bond-donating heterocycle, pyrazole has been used as a more lipophilic and metabolically more stable bioisomer of phenol. Pyrazoles have attracted more and more attention due to their broad spectrum of action and strong efficacy.
Pyrazone
Custom pyrazone for customers from all over the world are our main business.

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IDRX-42
IDRx announces $120 million series B financing to advance potential best-in-class new treatment for gastrointestinal stromal tumor (GIST). IDRX-42 is a potent, oral, highly selective KIT inhibitor targeting all major categories of activating and resistance mutations in patients with KIT-mutant GIST (including variants in exons 9, 11, 13 and 17). IDRX-42 was granted Orphan Drug designation by the FDA for the treatment of GIST. IDRX-42 is currently being evaluated in StrateGIST 1, a first-in-human Phase 1/1b study.
In preclinical studies, IDRX-42 demonstrated superior antitumor activity compared to imatinib, the current first-line of therapy, in GIST human xenograft models expressing mutations in KIT exons 9 and 11. In xenograft models expressing secondary resistance mutations in KIT exon 13 or 17, IDRX-42 treatment resulted in potent and dose-dependent antitumor activity superior to the second-line standard of care agent, sunitinib.