Название продукции:2-Amino-9-((2R,3R,4S)-3,4-bis(hydroxymethyl)oxetan-2-yl)-1H-purin-6(9H)-one
IUPAC Name:2-amino-9-[(2R,3R,4S)-3,4-bis(hydroxymethyl)oxetan-2-yl]-6,9-dihydro-1H-purin-6-one
- CAS：113269-46-8
- Молекулярная формула：C10H13N5O4
- Чистота：97%
- Номер в каталоге：CM259587
- Молекулярная масса：267.25
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Информация о продукции
- Номер CAS:113269-46-8
- Молекулярная формула:C10H13N5O4
- Точка плавления:-
- Smiles-код:O=C1NC(N)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@H]3CO
- Плотность:
- Номер в каталоге:CM259587
- Молекулярная масса:267.25
- Точка кипения:
- Номер Mdl:
- Хранение:
Category Infos
- Purines
- Purines are heterocyclic aromatic compounds composed of linked pyrimidine and imidazole rings. In mammals, purines are most commonly expressed in DNA and RNA (including the purines adenine and guanine), as well as single-molecule nucleotides (adenosine triphosphate (ATP), adenosine diphosphate (ADP), adenosine monophosphate (AMP), cyclic AMP, and to a lesser extent guanosine triphosphate (GTP) and cyclic guanosine monophosphate (cGMP). Purines are also key elements of the following energy metabolism molecules: reduced nicotinamide adenine dinucleotide, nicotinamide adenine dinucleotide phosphate (NADPH), and coenzyme Q. Purines can also act as direct neurotransmitters; for example, adenosine may interact with receptors to modulate cardiovascular and central nervous system (CNS) function.
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- Oxetanes
- Oxygen heterocycles are one of the most common heterocycles in drugs and natural products. Oxetene has high polarity and is also a good acceptor for hydrogen bond, which contributes to the metabolism and chemical stability of its host molecules. When substituted for commonly used functional groups such as gem dimethyl or carbonyl, oxetane units can induce profound changes in water solubility, lipophilicity, metabolic stability and conformational preference. Four of the FDA-approved drugs contain oxetenes: Orlistat, Paclitaxel, and two of its derivatives, Docetaxel and Cabazitaxel. Currently, oxetane-containing building blocks are flourishing in medicinal chemistry and drug discovery.
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