Название продукции:methyl 5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazole-4-carboxylate

IUPAC Name:methyl 5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazole-4-carboxylate

CAS:1103500-32-8
Молекулярная формула:C15H12F3NO4
Чистота:95%
Номер в каталоге:CM327352
Молекулярная масса:327.26

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CM327352-5g 6-7 Weeks ǺǺœŸ

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Информация о продукции

Номер CAS:1103500-32-8
Молекулярная формула:C15H12F3NO4
Точка плавления:-
Smiles-код:O=C(C1=C(C2CC2)ON=C1C3=CC=CC=C3OC(F)(F)F)OC
Плотность:
Номер в каталоге:CM327352
Молекулярная масса:327.26
Точка кипения:
Номер Mdl:
Хранение:

Category Infos

Cyclopropanes
Cyclopropane is the smallest cyclic compound with unique structural features and physicochemical properties, which is widely used in the design of small molecule drugs. In drug design, it is often used to increase activity, fix conformation and improve PK and water solubility. The introduction of cyclopropyl groups into drugs can change various properties of molecules, such as improving metabolic stability; increasing biological activity; enhancing drug efficacy; limiting polypeptide conformation and slowing down its hydrolysis; reducing plasma clearance; improving drug dissociation and many more. Cyclopropane rings are widely found in marketed drugs, including cardiovascular drugs, central nervous system (CNS) drugs, anticancer drugs, autoimmune and anti-inflammatory drugs.
Isoxazoles
Isoxazole is a liquid heterocyclic compound C3H3NO isomeric with oxazole and having a penetrating odor like that of pyridine. Isoxazoles belong to an important class of five-membered aromatic heterocycles containing two electronegative heteroatoms, nitrogen and oxygen, in a 1,2-relationship and three regular sp2 carbon atoms. These molecules are found to be key components in various synthetic products in daily use and also present as a pharmacophore essential for biological activity in many drugs and bioactive natural products. In addition, isoxazoles have demonstrated their ability to exhibit hydrogen bond donor/acceptor interactions with a variety of enzymes and receptors.

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