Thiazoles are very important functional groups in medicinal chemistry. They act as ligands on a variety of biological matrices. Thiazoles are used in a wide range of therapeutic applications, such as antibacterial, antiretroviral, antifungal, antiallergic, antihypertensive, pain treatment, and to control symptoms of schizophrenia.
Thiazolopyridines are a class of heterocyclic compounds. Thiazolopyridines were developed as allosteric inhibitors of MALT1 with good cellular potency and refined selectivity.